Akman 2007
Akman, A., Durusoy, C., Senturk, M., Koc, C. K., Soyturk, D., Alpsoy, E.Treatment of acne with intermittent and conventional isotretinoin: A randomized, controlled multicenter study. Archives of Dermatological Research, 2007, 299(10):467–73 [PMC free article: PMC2094720] [PubMed: 17710426]
Bossuyt 2003
Bossuyt, L., Bosschaert, J., Richert, B., Cromphaut, P., Mitchell, T., Al Abadie, M., Henry, I., Bewley, A., Poyner, T., Mann, N., Czernielewski, J.Lymecycline in the treatment of acne: An efficacious, safe and cost-effective alternative to minocycline. European Journal of Dermatology, 2003, 13(2):130–5 [PubMed: 12695127]
Braathen 1984
Braathen, L. R.Topical clindamycin versus oral tetracycline and placebo in acne vulgaris. Scandinavian Journal of Infectious Diseases, 1984, 43:71–5 [PubMed: 6242073]
Chen 2015
Chen, X., Song, H., Chen, S., Zhang, J., Niu, G., Liu, X.Clinical efficacy of 5-aminolevulinic acid photodynamic therapy in the treatment of moderate to severe facial acne vulgaris. Experimental and Therapeutic Medicine, 2015, 10(3):1194–8 [PMC free article: PMC4533172] [PubMed: 26622463]
Degreef 1982b
Degreef, H., VandenBussche. G.Double-blind evaluation of miconazole-benzoyl peroxide combination for the topical treatment of acne vulgaris. Dermatologica, 1982, 164(3):201–8 [PubMed: 6211379]
Del Rosso 2007
Del Rosso, J. Q.Truncal acne vulgaris: the relative roles of topical and systemic antibiotic therapy. Journal of Drugs in Dermatology, 2007, 6(2):148–51 [PubMed: 17373173]
Dhaked 2016
Dhaked, D. R., Meena, R. S., Maheshwari, A., Agarwal, U. S., Purohit, S.A randomized comparative trial of two low-dose oral isotretinoin regimens in moderate to severe acne vulgaris. Indian Dermatology Online Journal, 2016, 7(5):378–85 [PMC free article: PMC5038098] [PubMed: 27730033]
Dhawan 2013
Dhawan, S. S., Gwazdauskas, J.Clindamycin phosphate 1.2%-benzoyl peroxide (5% or 2.5%) plus tazarotene cream 0.1% for the treatment of acne. Cutis, 2013, 91(2):99–104 [PubMed: 23513559]
Dobson 1980
Dobson, R. L., Belknap, B. S.Topical erythromycin solution in acne. Results of a multiclinic trial. Journal of the American Academy of Dermatology, 1980, 3(5):478–82 [PubMed: 6452463]
Dogra 2020
Dogra, S., Sumathy, T. K., Nayak, C., Ravichandran, G., Vaidya, P. P., Mehta, S., Mittal, R., Mane, A., Charugulla, S. N.Efficacy and safety comparison of combination of 0.04% tretinoin microspheres plus 1% clindamycin versus their monotherapy in patients with acne vulgaris: a phase 3, randomized, double-blind study. Journal of Dermatological Treatment, 2020,1–9 [PubMed: 32020824]
Dreno 2017
Dréno, B., Tan, J., Rivier, M., Martel, P., Bissonnette, R.Adapalene 0.1%/benzoyl peroxide 2.5% gel reduces the risk of atrophic scar formation in moderate inflammatory acne: a split-face randomized controlled trial. Journal of the European Academy of Dermatology and Venereology, 2017, 31(4):737–742 [PubMed: 27790756]
Dreno 2018
Dréno, B., Bissonnette, R., Gagné-Henley., A., Barankin, B., Lynde, C., Kerrouche, N., Tan, J.Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison. American Journal of Clinical Dermatology, 2018, 19(2):275–286 [PMC free article: PMC5978908] [PubMed: 29549588]
Dubertret 2003
Dubertret, L., Alirezai, M., Rostain, G., Lahfa, M., Forsea, D., Dimitrie Niculae, B., Simola, M., Horvath, A., Mizzi, F.The use of lymecycline in the treatment of moderate to severe acne vulgaris: A comparison of the efficacy and safety of two dosing regimens. European Journal of Dermatology, 2003, 13(1):44–8 [PubMed: 12609781]
fa*ghihi 2017
fa*ghihi, G., Mokhtari, F., Fard, N. M., Motamedi, N., Hosseini, S. M.Comparing the efficacy of low dose and conventional dose of oral isotretinoin in treatment of moderate and severe acne vulgaris. Journal of Research in Pharmacy Practice, 2017, 6(4):233–8 [PMC free article: PMC5787910] [PubMed: 29417084]
Feldman 2013; Trial 1
Feldman, S. R., Werner, C. P., Alio Saenz, A. B.The efficacy and tolerability of tazarotene foam, 0.1%, in the treatment of acne vulgaris in 2 multicenter, randomized, vehicle-controlled, double-blind studies. Journal of Drugs in Dermatology, 2013, 12(4):438–46 [PubMed: 23652892]
Feldman 2013; Trial 2
Feldman, S. R., Werner, C. P., Alio Saenz, A. B.The efficacy and tolerability of tazarotene foam, 0.1%, in the treatment of acne vulgaris in 2 multicenter, randomized, vehicle-controlled, double-blind studies. Journal of Drugs in Dermatology, 2013, 12(4):438–46. [PubMed: 23652892]
Fugere 1990
Fugere, P., Percival-Smith, R. K., Lussier-Cacan, S., Davignon, J., Farquhar, D.Cyproterone acetate/ethinyl estradiol in the treatment of acne. A comparative dose-response study of the estrogen component. Contraception, 1990, 42(2):225–34 [PubMed: 2150795]
Gratton 1982
Gratton, D., Raymond., G. P., Guertin-Larochelle, S., Maddin, S. W., Leneck, C. M., Warner, J., Collins, J. P., Gaudreau, P., Bendl, B. J.Topical clindamycin versus systemic tetracycline in the treatment of acne. Results of a multiclinic trial. Journal of the American Academy of Dermatology, 1982, 7(1):50–3 [PubMed: 6213682]
Jones 1981
Jones, E. L., Crumley, A. F.Topical erythromycin vs blank vehicle in a multiclinic acne study. Archives of Dermatology, 1981, 117(9):551–3 [PubMed: 6457568]
Jones 2002
Jones, T., Mark, L., Monroe, E., Weiss, J., Levy, S.A multicentre, double-blind, parallel-group study to evaluate 3% erythromycin/5% benzoyl peroxide dual-pouch pack for acne vulgaris. Clinical Drug Investigation, 2002, 22(7):455–62
Kapadia 2005
Kapadia, N. F., Khalid, G., Burhany, T., Nakhoda, T.Comparative efficacy and safety and efficacy of systemic 13-cis retinoic acid 20mg/day vs. 40mg/day in acne vulgaris. Journal of Pakistan Association of Dermatologists, 2005, 15: 238–41
Khanna 1993
Khanna, N.Treatment of acne vulgaris with oral tetracylines. Indian Journal of Dermatology, Venerology and Leprology, 1993, 59(2):74–6
Kim 2017
Kim, T. I., Ahn, H. J., Kang, I. H., Jeong, K. H., Kim, N. I., Shin, M. K.Nonablative fractional laser-assisted daylight photodynamic therapy with topical methyl aminolevulinate for moderate to severe facial acne vulgaris: Results of a randomized and comparative study. Photodermatology Photoimmunology and Photomedicine, 2017, 33(5):253–9 [PubMed: 28500784]
Kuhlman 1986
Kuhlman, D. S., Callen, J. P.A comparison of clindamycin phosphate 1 percent topical lotion and placebo in the treatment of acne vulgaris. Cutis, 1986, 38(3):203–6 [PubMed: 2945704]
Lassus 1984
Lassus, A., Juvakoski, T., Lauharanta, J.Motretinide versus benzoyl peroxide in the treatment of acne vulgaris. Dermatologica, 1984, 168(4):199–201 [PubMed: 6233188]
Leyden 2018
Leyden, J. J., Sniukiene, V., Berk, D. R., Kaoukhov, A.Efficacy and Safety of Sarecycline, a Novel, Once-Daily, Narrow Spectrum Antibiotic for the Treatment of Moderate to Severe Facial Acne Vulgaris: Results of a Phase 2, Dose-Ranging Study. Journal of Drugs in Dermatology, 2018, 17(3):333–8 [PubMed: 29537451]
Mei 2013
Mei, X., Shi, W., Piao, Y.Effectiveness of photodynamic therapy with topical 5-aminolevulinic acid and intense pulsed light in Chinese acne vulgaris patients. Photodermatology Photoimmunology and Photomedicine, 2013, 29(2):90–6 [PubMed: 23458393]
Miller 1986b
Miller, J. A., Wojnarowska, F. T., Dowd, P. M.Anti-androgen treatment in women with acne: A controlled trial. British Journal of Dermatology, 1986, 114(6):705–16 [PubMed: 2941052]
Moore 2018; Trial 1
Moore, A., Green, L. J., Bruce, S., Sadick, N., Tschen, E., Werschler, P., Cook-Bolden, F. E., Dhawan, S. S., Forsha, D., Gold, M. H., et al. Once-Daily Oral Sarecycline 1.5 mg/kg/day Is Effective for Moderate to Severe Acne Vulgaris: results from Two Identically Designed, Phase 3, Randomized, Double-Blind Clinical Trials. Journal of Drugs in Dermatology, 2018, 17(9):987–96 [PubMed: 30235387]
Moore 2018; Trial 2
Moore, A., Green, L. J., Bruce, S., Sadick, N., Tschen, E., Werschler, P., Cook-Bolden, F. E., Dhawan, S. S., Forsha, D., Gold, M. H., et al. Once-Daily Oral Sarecycline 1.5 mg/kg/day Is Effective for Moderate to Severe Acne Vulgaris: results from Two Identically Designed, Phase 3, Randomized, Double-Blind Clinical Trials. Journal of Drugs in Dermatology, 2018, 17(9):987–96 [PubMed: 30235387]
Pariser 2005
Pariser, D. M., Thiboutot, D. M., Clark, S. D., Jones, T. M., Liu, Y., Graeber, M.The efficacy and safety of adapalene gel 0.3% in the treatment of acne vulgaris: A randomized, multicenter, investigator-blinded, controlled comparison study versus adapalene gel 0.1% and vehicle. Cutis, 2005, 76(2):145–51 [PubMed: 16209161]
Pariser 2014
Pariser, D. M., Rich, P., Cook-Bolden, F. E., Korotzer, A.An aqueous gel fixed combination of clindamycin phosphate 1.2% and benzoyl peroxide 3.75% for the once-daily treatment of moderate to severe acne vulgaris. Journal of Drugs in Dermatology, 2014, 13(9):1083–9. [PubMed: 25226009]
Pariser 2016
Pariser, D. M., Eichenfield, L. F., Bukhalo, M., Waterman, G., Jarratt, M., Bhatia, A., Greenstein, D., Hamzavi, F., Kantor, J., Speelman, P. N., Murakawa, G. J., Tichy, E., Zaengelin, A., Frankel, E., Werschler, W.Photodynamic therapy with methyl aminolaevulinate 80 mg g−1 for severe facial acne vulgaris: a randomized vehicle-controlled study. British Journal of Dermatology, 2016, 174(4):770–7 [PubMed: 26663215]
Parsad 2001
Parsad, D., Pandhi, R., Nagpal, R., Negi, K. S.Azithromycin monthly pulse vs daily doxycycline in the treatment of acne vulgaris. Journal of Dermatology, 2001, 28(1):1–4 [PubMed: 11280457]
Richter 1998a
Richter, J. R., Bousema, M. T., De Boulle, Klvm., Degreef, H. J., Poli, F.Efficacy of a fixed clindamycin phosphate 1.2%, tretinoin 0.025% gel formulation (Velac) in the topical control of facial acne lesions. Journal of Dermatological Treatment, 1998, 9(2):81–90
Sami 2008
Sami, N. A., Attia, A. T., Badawi, A. M.Phototherapy in the treatment of acne vulgaris. Journal of Drugs in Dermatology, 2008, 7(7):627–32 [PubMed: 18664153]
Schmidt 2011
Schmidt, N., Gans, E. H.Clindamycin 1.2% tretinoin 0.025% gel versus clindamycin gel treatment in acne patients: A focus on fitzpatrick skin types. Journal of Clinical and Aesthetic Dermatology, 2011, 4(6):31–40 [PMC free article: PMC3140902] [PubMed: 21779414]
Sklar 1996
Sklar, J. L., Jacobson, C., Rizer, R., Gans, E. H.Evaluation of Triaz 10% Gel and Benzamycin in acne vulgaris. Journal of Dermatological Ttreatment, 1996, 7(3):147–52
Stein Gold 2008
Stein Gold, L., Colon, L. E., Johnson, L. A., Gottschalk, R. W.Is switching retinoids a sound strategy for the treatment of acne vulgaris?Journal of Drugs in Dermatology, 2008, 7(6 Suppl):11–7 [PubMed: 18575221]
Stein Gold 2016
Stein Gold, L., Weiss, J., Rueda, M.J., Liu, H. and Tanghetti, E., 2016. Moderate and severe inflammatory acne vulgaris effectively treated with single-agent therapy by a new fixed-dose combination adapalene 0.3%/benzoyl peroxide 2.5% gel: a randomized, double-blind, parallel-group, controlled study. American Journal of Clinical Dermatology, 2016, 17(3), 293–303 [PMC free article: PMC4863916] [PubMed: 26945741]
Stewart 2006
Stewart, D. M., Torok, H. M., Weiss, J. S., Plott, R. T.Dose-ranging efficacy of new once-daily extended-release minocycline for acne vulgaris. Cutis, 2006, 78(4 Suppl):11–20 [PubMed: 17436825]
Strauss 1984a
Strauss, J. S., Rapini, R. P., Shalita, A. R., Konecky, E., Pochi, P. E., Comite, H., Exner, J. H.Isotretinoin therapy for acne: Results of a multicenter dose-response study. Journal of the American Academy of Dermatology, 1984, 10(3):490–6 [PubMed: 6233335]
Tanghetti 2006
Tanghetti, E. A., W., Solomon, B., Loven, K., Shalita, A.Tazarotene versus tazarotene plus clindamycin/benzoyl peroxide in the treatment of acne vulgaris: a multicenter, double-blind, randomized parallel-group trial. Journal of Drugs in Dermatology, 2006, 5(3):256–61 [PubMed: 16573259]
Tanghetti 2011
Tanghetti, E., Dhawan, S., Green, L., Ling, M., Downie, J., Germain, M. A., Kasteler, J. S., Kircik, L., Oefelein, M. G., Draelos, Z.Clinical evidence for the role of a topical anti-inflammatory agent in comedonal acne: Findings from a randomized study of dapsone gel 5% in combination with tazarotene cream 0.1% in patients with acne vulgaris. Journal of Drugs in Dermatology, 2011, 10(7):783–92 [PubMed: 21720661]
Tanghetti 2019
Tanghetti, E. A., Kircik, L. H., Green, L. J., Guenin, E., Harris, S., Martin, G., Pillai, R.A Phase 2, Multicenter, Double-Blind, Randomized, Vehicle-Controlled Clinical Study to Compare the Safety and Efficacy of a Novel Tazarotene 0.045% Lotion and Tazarotene 0.1% Cream in the Treatment of Moderate-to-Severe Acne Vulgaris. Journal of Drugs in Dermatology, 2019, 18(6):542 [PubMed: 31251546]
Thiboutot 2002
Thiboutot, D., Jarratt, M., Rich, P., Rist, T., Rodriguez, D., Levy, S.A randomized, parallel, vehicle-controlled comparison of two erythromycin/benzoyl peroxide preparations for acne vulgaris. Clinical Therapeutics, 2002, 24(5):773–85 [PubMed: 12075945]
Thiboutot 2008
Thiboutot, D., Arsonnaud, S., Soto, P.Efficacy and tolerability of adapalene 0.3% gel compared to tazarotene 0.1% gel in the treatment of acne vulgaris. Journal of drugs in dermatology, 2008, 7(6 Suppl):3–10 [PubMed: 18575220]
Tyring 2018
Tyring, S. K., Kircik, L. H., Pariser, D. M., Guenin, E., Bhatt, V., & Pillai, R.Novel Tretinoin 0.05% Lotion for the Once-Daily Treatment of Moderate-to-Severe Acne Vulgaris: assessment of Efficacy and Safety in Patients Aged 9 Years and Older. Journal of Drugs in Dermatology, 2018, 17(10):1084–91 [PubMed: 30365589]
Zouboulis 2000
Zouboulis, C. C., Derumeaux, L., Decroix, J., Maciejewska-Udziela, B., Cambazard, F., Stuhlert, A.A multicentre, single-blind, randomized comparison of a fixed clindamycin phosphate/tretinoin gel formulation (Velac) applied once daily and a clindamycin lotion formulation (Dalacin T) applied twice daily in the topical treatment of acne vulgaris. British Journal of Dermatology, 2000, 143(3):498–505 [PubMed: 10971320]
